27th ISMRM Annual Meeting • 11-16 May 2019 • Montréal, QC, Canada

Sunrise Session
Connectivity for Clinical Study

Back to Program-at-a-Glance

Connectivity for Clinical Study
Sunrise Session

ORGANIZERS: Masaaki Hori, Ivana Drobnjak, Dmitry Novikov

Tuesday, 14 May 2019
Room 510A-D  07:00 - 08:00 Moderators:  Toshiaki Taoka, Masaaki Hori

Skill Level: Intermediate

Session Number: S-TU-04

This course will demonstrate the potential utility of connectivity for clinical situation.

Target Audience
Scientists and clinicians interested in applications of connectivity for clinical study.

Educational Objectives
As a result of attending this course, participants should be able to:
-Describe the basics of connectivity analysis in vivo data and potential pitfalls; and
-List the types of tissue changes that may be detected by connectivity analysis in the brain.


  Concepts of Connectivity
Mara Cercignani
This paper will introduce the concept of connectivity and how it can be measured using MRI data. Potential pitfalls will also be reviewed

  Diffusion MRI-Based Connectomics Study in Neurodegenerative Diseases
Video Permission Withheld
Koji Kamagata
Neurodegenerative diseases are a group of chronic, progressive disorders that are characterized by the gradual loss of neurons in various areas of the central nervous system. The onset and progression of neurodegeneration are closely linked to brain network degeneration via demyelination, axonal degeneration, and dendrite retraction. The pathophysiology is also characterized by “prion-like” abnormal protein aggregation and its propagation along neural connections. Connectomic analysis, the comprehensive mapping of neural connections within the brain, may thus provide novel ways to characterize neurodegenerative diseases. Here, we introduce the clinical application of connectomics in neurodegenerative diseases including Alzheimer’s and Parkinson’s.

Back to Program-at-a-Glance   |   Back to Top
The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.