27th ISMRM Annual Meeting • 11-16 May 2019 • Montréal, QC, Canada

Sunrise Session
Quantitative MRI: Diffusion & Flow

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Quantitative MRI: Diffusion & Flow
Sunrise Session

ORGANIZERS: José Marques, Sebastian Kozerke, Ileana Hancu

Tuesday, 14 May 2019
Room 513D-F  07:00 - 08:00 Moderators:  Rita Nunes, Sebastian Kozerke

Skill Level: Intermediate to Advanced

Session Number: S-TU-08

Extend the understanding of the MR signal evolution beyond the simple phenemenological single-pool relaxation models. 

During this educational course, the role of tissue physical properties such as magnetic susceptibility and electric conductivity and how they affect imaging and relaxation processes will be addressed. Furthermore, the role of diffusion, perfusion, flow in the observed signal and how they can be encoded and measured in MRI will be discussed.

Target Audience
Scientists who are interested in developing/improving quantitative MR approaches.

Educational Objectives
As a result of attending this course, participants should be able to:
- Develop MR pulse sequence design to implement practical encoding approaches of the various physical properties of tissues;
- Apply decoding equation/reconstruction to calculate tissue magnetic susceptibility, electrical conductivity, relaxation, diffusion, perfusion, flow; and
- Compare various software solutions for data reconstruction/processing.


  Incoherent vs. Coherent Motion
Andreas Wetscherek
Target audience: Researchers interested in the characterization of perfusion using contrast-free methods, such as measuring intravoxel incoherent motion using diffusion-weighted MRI.

Participants will develop a deep understanding of the effects of applied magnetic field gradients on the transverse magnetization of particles undergoing motion / flow and the implications on the magnitude and phase of the measured MRI signal. Topics include gradient moments, velocity encoding (VENC), the intravoxel incoherent motion (IVIM) model, the Gaussian phase approximation, flow-compensation / higher order moment nulling and oscillating gradients / temporal diffusion spectroscopy.

  Sequences & Analysis
Did Not Present
Magalie Viallon
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The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.