27th ISMRM Annual Meeting • 11-16 May 2019 • Montréal, QC, Canada

Combined Educational & Scientific Session
Stroke: Early Signs & Late Recovery

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Stroke: Early Signs & Late Recovery
Combined Educational & Scientific Session

ORGANIZERS: Meiyun Wang, Andre Obenaus

Wednesday, 15 May 2019
Room 513A-C  13:30 - 15:30 Moderators:  Yan Bai, Meiyun Wang

Skill Level: Basic to Advanced

Session Number: W-05

Stroke is one of the leading cause of deaths in the world. This combined scientific and educational session focuses on the applications of advanced MRIs in the early diagnosis, guiding therapy, and evaluation of late functional recovery in stroke.

Target Audience
Trainees and scientists, as well as neuroradiologists, neurologists, and other clinical professionals interested in understanding the latest developments in stroke imaging.

Educational Objectives
As a result of attending this course, participants should be able to:
- Discuss early diagnosis and evaluation of stroke using neuroimaging;
- Describe how the brain re-organizes during functional recovery; and
- Discuss current and emerging imaging techniques.


Assessment of Functional Recovery After Stroke: Connectivity
Arno Villringer
Symptoms after stroke are not only determined by location and extent of a lesion, but also by alterations of connectivity. Such changes have been assessed with functional connectivity MRI (fcMRI) based on resting-state recordings. Here, different fcMRI approaches are reviewed ranging from interhemispheric connectivity in one network, simultaneous assessment of many networks to methods based on graph theory. A recent approach overcomes the notion of “fixed separate connectivity networks” but assumes a multidimensional connectivity space (Margulies et al. PNAS 2016). As a perspective, fcMRI will allow to tailor brain stimulation therapies to the pathophysiological state of the individual patient.  

Mapping Asymmetrically Prominent Cortical Veins & Microbleeds Using SWI & QSM
E. Mark Haacke
Intracranial Collaterals: The Role of MRI
Xin Lou
Studies have found collateral circulation was correlated with progression of stroke and clinical outcome. Many advanced imaging approaches appeared regarding the intracranial collaterals, including DSA, CT and MR. Specifically, the newly developed MR sequences, including multiphase contrast enhanced MR angiography, ASL and vessel-encoded ASL etc. have been used in the visualization of collaterals. Additionally, some conventional MR sequences have also been found useful. Learning what MR can do in the field of collaterals is of paramount importance. Application of MR techniques in intracranial collaterals may help elucidate pathophysiological characteristics of collaterals and enhance the therapeutic and prognostic performance in stroke patients.

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