27th ISMRM Annual Meeting • 11-16 May 2019 • Montréal, QC, Canada

Weekend Educational Session
MRI Data Acquisition: Pulse Sequences

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MRI Data Acquisition: Pulse Sequences
Weekend Course

ORGANIZERS: Fernando Boada, Douglas Noll, Neville Gai

Sunday, 12 May 2019
Room 520A-F  08:00 - 11:30 Moderators:  Xiaohong Joe Zhou, Suchandrima Banerjee

Skill Level: Basic to Advanced

Session Number: WE-14

This course describes the basic principles for the generation of the MRI signal/contrasts and their corresponding spatial encoding together with the broad categories grouping the most important and heavily used pulse sequences.

Target Audience
MRI scientists interested in understanding and implementing MRI pulse sequences and clinicians seeking to understand the basic features and properties of common MRI pulse sequences.

Educational Objectives
As a result of attending this course, participants should be able to:
- Explain the fundamental concepts related to the generation and spatial encoding of the MRI signal; and
- Describe the differences between the magnetization preparation and signal acquisition components of a pulse sequence.


RF Excitation & Parallel Transmission
William Grissom
RF excitation is a necessary ingredient to all pulse sequences. This lecture will introduce common RF pulse types, the mechanics behind their function, and practical uses for them. The goal of this lecture is to give the pulse sequence designer the knowledge necessary to make appropriate RF pulse selections in a wide variety of applications.

  Signal Generation & Spatial Encoding
David Higgins
Basic MR physics will be reviewed, to provide a foundation for discussion of more advanced concepts in the course. The process of spatial encoding of the MR signal, from signal generation to image reconstruction, will be described. The the information content of k-space will be illustrated and discussed. Routine adjustments which are made to k-space data will be introduced.

  Encoding Basic Physiological Processes into the MRI Signal: Motion & Flow
Pelin Aksit Ciris
MRI can be used to non-invasively encode and quantify different biophysical aspects of tissue including flow and motion. In this presentation, we will review methods that generate motion related image contrast, through manipulation of longitudinal magnetization prior to excitation, such as Time-of-flight MR Angiography, Arterial Spin Labeling, Myocardial Tagging; as well as through manipulation of transverse magnetization between excitation and acquisition, such as Phase Contrast MR Angiography, Diffusion Imaging, and MR Elastography.

  Break & Meet the Teachers
  Single-Shot Sequences
Video Permission Withheld
Xiaohong Joe Zhou
Single-shot pulse sequences are a class of sequences that can rapidly traverse k-space in a single repetition time (TR), producing sufficient k-space data for image reconstruction. In this lecture, we will highlight four single-shot pulse sequences, including echo planar imaging (EPI), turbo-spin echo (TSE) or fast spin echo (FSE), gradient and spin echo (GRASE), and spiral. For each pulse sequence, we will describe the spin physics involved, discuss several “tricks” in practical implementation, present strategies to mitigate image artifacts, and provide examples in clinical and research applications. 

  Multi-Shot & Multi-Echo Techniques
Video Permission Withheld
Daniel Herzka
  Faster & Higher Quality MRI Through Tailored Undersampling
Kawin Setsompop
Various image reconstruction approaches (e.g. parallel imaging, CS, ML) have been developed to enable k-space under-sampling. Optimal performance for these reconstruction approaches at high accelerations requires a tailored sampling scheme. In this course, we will examine these sampling strategies and how to adopt them effectively in a wide variety of imaging sequences under various constraints. Insights on how to flexibly take advantage of the undersampling for either scan time reduction and/or artifact mitigation will be discussed. Examples will be provided to demonstrate the benefit of a synergistic design approach on sampling, sequence, and reconstruction. 

  Lunch & Meet the Teachers
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