27th ISMRM Annual Meeting • 11-16 May 2019 • Montréal, QC, Canada

Weekend Educational Session
MSK Disease: Current Status & Potential Applications of Advanced Imaging

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MSK Disease: Current Status & Potential Applications of Advanced Imaging - Morning & Afternoon
Weekend Course

ORGANIZERS: Jung-Ah Choi, Emily McWalter, Riccardo Lattanzi, Miika Nieminen, Edwin Oei, Jan Fritz

Sunday, 12 May 2019
Room 513A-C  08:00 - 11:50 Moderators:  Chiara Giraudo, Jan Fritz

Skill Level: Intermediate

Session Number: WE-18AB

The aim of this session is to bring together clinicians and scientists to learn about and discuss current MR imaging practice and unmet imaging needs of musculoskeletal diseases including muscle disorders, musculoskeletal complications of diabetes, inflammatory arthropathy, osteoarthritis, sports injuries, osteochondrosis, and osteonecrosis. Promising advanced MRI techniques will also be proposed.

Target Audience
Radiologists, clinicians, technologists, and scientists interested in translational research.

Educational Objectives
As a result of attending this course, participants should be able to:
- Describe the disease(s) and summarize the current standard imaging techniques;
- Identify the current unmet imaging needs of several musculoskeletal diseases; and
- Discuss potential solutions based on novel/advanced imaging techniques.


  Muscle Disorders: Present
Pierre Carlier
  Muscle Disorders: Future
Eric Sigmund
(placeholder; syllabus currently pending)

  MSK Complications of Diabetes: Present
Mark Schweitzer
1. Pathophysiology of DM

2. Why MSK system?

3. tendons

4. ligaments

5. joints

6. osteomyelitis

  Self Assessment Module (SAM)
  MSK Complications of Diabetes: Future
Prodromos Parasoglou
  Break & Meet the Teachers
  Inflammatory Arthropathy: Present
Tamotsu Kamishama

  Inflammatory Arthropathy: Future
Chiara Giraudo
This lecture is for radiologists and clinicians, technologists, and scientists interested in musculoskeletal imaging with a special focus on inflammatory rheumatic diseases. The presentation will address how we may improve the diagnostic process in adults and pediatric patients affected by this heterogeneous group of inflammatory arthropathies. It will be discussed not only how the MR protocols can be further optimized considering the constant new technological improvements but also the role of hybrid imaging applying PET/MR. Indeed, PET/MR combining specific tracers and sequences via a whole-body approach may provide simultaneously acquired metabolic, functional and anatomical information characterizing the injured areas at diagnosis and after treatment. Furthermore, the role and application of qualitative and quantitative analyses will be addressed, including the use of machine learning and the assessment of radiomics features in the era of biological therapy.In conclusion, after this presentation, the audience should have a comprehensive overview about promising novel MR and PET/MR applications and the research aspectsthat should be further investigated in inflammatory arthropathies.

  Osteoarthritis: Present
Alissa Burge
Osteoarthritis is an extremely common cause of morbidity, affecting an estimated 30.8 million adults in the united states, and is cited as the 5th most common cause of disability and the most prevalent form of musculoskeletal pathology worldwide, contributing to tremendous human and economic burden.  MR imaging can provide valuable information regarding a variety of characteristics relevant to the natural history of osteoarthritis, including risk factors, diagnosis and severity of disease, and complications of both disease and treatment, thereby facilitating clinical decision making.

  Osteoarthritis: Future
Stefan Zbyn
Compositional MRI techniques have gained increasing attention in Osteoarthritis (OA) research over the recent years, as they allow detection of early biochemical alteration in musculoskeletal tissues prior to appearance of the morphological changes. This presentation will provide an overview of basic technical principles, biochemical correlates, recent technical developments and in vivoapplications of compositional MRI techniques for early detection, monitoring and prediction of OA progression in the knee joint.

  Lunch & Meet the Teachers
  Sports Injuries: Present
Haron Obaid
This talk will focus on MRI imaging techniques as related to sports injuries, role of MRI in sports imaging-problem solving tool, pitfalls and limitations of MRI in sports imaging. There will be a review of imaging findings of common injury patterns affecting the tendons, ligaments, cartilage, muscles and bones.

  Sports Injuries: Advanced Imaging Methods for Injuries to Short-T2 Tissues
Ashley Williams
Sprains, strains, tears and stress fractures are unfortunately common occurrences in athletes and weekend warriors alike.  Detection and quantitation of subtle and, in some cases, subclinical damage to short-T2 tissues using advanced MRI methods, like ultrashort echo time (UTE) and zero echo time (ZTE) imaging, may help to guide the clinical management of injured patients as they recover and return to sport. Audience members will be introduced to common sports injuries involving short-T2 tissues and new and upcoming MRI techniques to diagnose, stage, and monitor tissue injury and recovery by assessing short-T2 tissue properties.

  Break & Meet the Teachers
  Osteonecrosis & Osteochondrosis: Present
Mihra Taljanovic
This talk reviews the pathophysiology, clinical findings, imaging findings and treatment options of epiphyseal osteonecrosis, bone infarcts and various types of osteohondroses with emphasis on magnetic resonance imaging (MRI). Specifically, osteonecrosis of the femoral head, humeral head, talar dome, lunate and proximal scaphoid pole will be discussed. Steinberg modified FICAT classification of the femoral head osteonecrosis and Lichtman staging of Kienbock Disease will be presented in tables. Following osteochondroses will be addressed:  Legg-Calvé-Perthes disease, osteochondritis dissecans (OCD), osteochondrosis of the capitellum (Panner disease), Blount disease (tibia vara) Osgood-Schlatter disease, Sinding-Larsen-Johansson disease (jumper’s knee), Freiberg infraction, Köhler disease and Scheuermann’s disease.

  Osteochondrosis & Osteonecrosis: Future Musculoskeletal Imaging Applications for Pediatric and Young Adult Patients
Jutta Ellermann
Advanced qualitative and quantitative MRI methods can be utilized to study unique aspects of the developing skeleton that are important for diagnosis and better treatment of musculoskeletal diseases of pediatric and young adult patients.

  Adjournment & Meet the Teachers
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