27th ISMRM Annual Meeting • 11-16 May 2019 • Montréal, QC, Canada

Weekend Educational Session
Basics of Molecular Dynamic Sensitive MRI; MT, CEST & Rotating-Frame Relaxation

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Basics of Molecular Dynamic Sensitive MRI; MT, CEST & Rotating-Frame Relaxation
Weekend Course


Sunday, 12 May 2019
  08:00 - 12:00 Moderators:  Greg Stanisz, Jiadi Xu

Skill Level: Basic to Intermediate

Session Number: WE-19

This course will cover the mechanisms, acquisition strategies, quantification methods and applications of methods sensitive to molecular dynamics. These techniques offer unique contrasts to assess biological processes and diseases not possible with standard contrasts. In particular, the lecturers will covers topics on magnetization transfer (MT), chemical exchange saturation transfer (CEST), rotating frame relaxation methods (T1rho, T2rho & RAFF).

Target Audience
Basic scientists and clinicians who desire an introduction to exchange-based and molecular dynamics methods and applications.

Educational Objectives
As a result of attending this course, participants should be able to:
- Explain the acquisition and quantification methods used for each of the methods covered in the lectures;
- Describe the potential pitfalls related to the acquisition and interpretation of the results;
- Identify applications that would benefit from the methods covered; and
- Illustrate what the measurements mean in terms of the specific biomedical application.


  Quantitative Magnetization Transfer Imaging for Characterizing Pathology
Seth Smith
  CEST MRI for Beginners
Eleni Demetriou
  The Basics of Rotating Frame Relaxation (T1rho, T2rho)
Elena Vinogradov
  Break & Meet the Teachers
  Exploiting Rotation Along Fictitious Fields
Silvia Mangia
  Imaging Molecular Dynamics & Its Clinical Applications in the Brain
Lucio Frydman
  Role of Molecular Dynamic Imaging in Musculoskeletal Applications
Mikko Nissi
  Lunch & Meet the Teachers
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The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.