Thalamic structural connectivity abnormalities in minimal hepatic encephalopathy: a probabilistic tractography study
Hua-Jun Chen1, Tian-Xiu Zou1, and Nao-Xin Huang1
1Fujian Medical University Union Hospital, Fuzhou, China
The altered thalamic structural connectivity with both
cortical and subcortical regions was found in MHE, which may underlie the mechanism about cognitive deficits and can serve
as biomarker for diagnosis of MHE and monitoring disease progression.
Figure 2. The
illustration of fiber connectivity between thalamus and cortical/subcortical subdivisions.
The thalamic connectivities of right hemisphere in one healthy volunteer are
shown here for visualization.
Figure 3. Between-group difference in connectivity strength. The markers *, †, and # respectively represent
significant differences between MHE vs HC, NHE vs HC, as well as MHE vs NHE. The FDR-corrected P values and
the effect size (EZ) are shown in the figure.