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Effects of calcification on blood-flow pulsatility variation along the internal carotid artery in small vessel disease patients, a 7T MRI study
Rick J van Tuijl1, Ynte M Ruigrok2, Irene C van der Schaaf1, Gabriël J. E. Rinkel2, Birgitta K Velthuis1, and Jaco J.M. Zwanenburg1
1Radiology, UMC Utrecht, Utrecht, Netherlands, 2Neurology and Neurosurgery, Rudolf Magnus Institute of Neuroscience, UMC Utrecht, Utrecht, Netherlands
Intracranial internal carotid artery (ICA) calcification contributes to an increased pulsatility over the ICA in the cerebral small vessel disease group compared to healthy controls. Pulsatility change along the ICA was influenced by calcification volume, age, hypertension, but not by sex.
Figure 1: vPI values for Healthy Control group, intracerebral hemorrhage and lacunar infarct (combined CSVD group) per segment.
Table 2: Velocity pulsatility index (vPI) values (mean ± SD) per segment of the ICA. N = number of vPI measurements per vessel and segment, percentage difference is calculated with respect to the value at the C1 segment.