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Comparison of ultrasound and magnetic resonance imaging for the detection of fetal corpus callosum abnormalities
Cong Sun1, Yufan Chen1, Jinxia Zhu2, and Guangbin Wang1
1Shandong Medical Imaging Research Institute, Shandong University, Jinan, China, 2MR Collaboration, Healthcare Siemens Ltd., Beijing, China, Beijing, China
MRI was significantly better than ultrasound in being able to diagnose normal and abnormal fetal CC. Also, fetal MRI can be helpful in assessing associated abnormalities and enhancing prognostic consultations.
Fig. 2. a-b, A fetus at 33 weeks of gestation with isolated complete absence of the corpus callosum (CACC). c-d A fetus at 30 weeks of gestation. CACC with a huge intra-hemispheric cyst. e, A fetus at 32 weeks of gestation with isolated splenium absence (PACC). f-h A fetus at 33 weeks of gestation. A partial absence of the CC (PACC) with pachygyria, and left front lobe leukodystrophy. i, A fetus at 28 weeks of gestation with isolated hypogenesis (HCC) and the CC is significantly thinner and shorter. J-l A fetus at 35 weeks of gestation. HCC with bilateral frontal lobe leukodystrophy.

Table 3. Diagnosing fetal CC abnormalities in the postnatal, ultrasound (US), and magnetic resonance imaging (MRI) diagnostic groups

Cor., correct diagnosis; Misdiag, misdiagnosis; Mis-FU, missed diagnosis Isolated CACC, Isolated complete agenesis of the corpus callosum; Isolated PACC, Isolated partial agenesis of the corpus callosum; Isolated HCC, Isolated hypoplasia of the corpus callosum; Non-isolated CACC, CACC with other malformations; Non-isolated PACC: PACC with other malformations; Non-isolated HCC: HCC with other malformations.