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Variable-density Fast-Spin-Echo (FSE) for volumetric inhomogeneous Magnetization Transfer (ihMT) imaging
Manuel Taso1, Fanny Munsch1, Arnaud Guidon2, Olivier M. Girard3, Guillaume Duhamel3, David C. Alsop1, and Gopal Varma1
1Division of MRI research, Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States, 2Global MR Applications and Workflow, GE Healthcare, Boston, MA, United States, 3CRMBM, Aix-Marseille Univ, CNRS, Marseille, France
Fast-Spin-Echo accelerated with variable-density k-space sampling and Compressed-Sensing allows for high SNR volumetric inhomogeneous magnetization transfer (ihMT) imaging of the brain. It has potential for high-resolution, but also imaging outside of the brain.
Figure 4 – Illustration of the image quality of the ihMT-FSE with three-plane reformats of the zero-power and ihMT volume, as well as multiple axial reformats of the ihMT volume
Figure 3 – Comparison between ihMT-RAGE, VD-FSE at two acceleration rates (the R≈5 is matched in acquisition time with the ihMT-RAGE, Tacq≈5'30", the R≈3.2 has a scan time of ≈11min) acquired at 1.8x1.8x2.5mm3