Gizem Temiz1, Sophie Sébille1, Chantal François1, Eric Bardinet1, and Carine Karachi1,2
1CENIR, Institut du Cerveau et de la Moelle Epinière, Paris, France, 2AP-HP, Hôpital de la Pitié-Salpêtrière, Department of Neurosurgery, Paris, France, Paris, France
1CENIR, Institut du Cerveau et de la Moelle Epinière, Paris, France, 2AP-HP, Hôpital de la Pitié-Salpêtrière, Department of Neurosurgery, Paris, France, Paris, France
Our aim is to analyze the tractography based sub-parcellisation of subthalamic regions. Motor cluster was located in the posterolateral STN, a limbic cluster located medially in the MSR, and a motor-limbic cluster located in between were observed.
Figure 1: Cortical streamlines for STN and MSR: A. for a HCP subject, and C. for a PD patient. Histograms for HCP dataset (B.) and for PD dataset (D.) showing averaged connectivity of different cortical areas to the STN and MSR. The percentages of mean streamline numbers connecting the different sensorimotor (green), associative (blue) and limbic (red) cortical areas to the STN (dark bars) and to the MSR (bright bars) are shown for the left hemisphere (LH).
Figure 2: 3D localization of the three cortical clusters in both the STN and MSR in native spaces A. for 6 HCP subjects, and B. for 6 PD patients