4532
High-resolution Distortion-free DWI of Pituitary Adenomas and Rathke Cleft Cysts Using Point-spread-function Encoded EPI
Jieying Zhang1, Chunjie Guo2, Xinrui Liu3, Yishi Wang1,4, Huimao Zhang2, and Hua Guo1
1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, 2Department of Radiology, the First Hospital of Jilin University, Changchun, China, 3Department of Neurosurgery, the First Hospital of Jilin University, Changchun, China, 4Philips Healthcare, Beijing, China
PSF-EPI can achieve high-resolution distortion-free DWI in the pituitary, in which two kinds of lesions show different features. PSE-EPI may help with the preoperative differentiation of pituitary lesions without contrast agent.
Figure 1: Images of patient 2 (female, 41-year-old) with an RCC in coronal view. The upper row shows the images of T2-TSE, non-DW PSF-EPI, mean DW PSF-EPI, non-DW SS-EPI and mean DW SS-EPI from left to right. In PSF-EPI, resolution = 1 x 1 x 2 mm3 and b-value = 800 mm/s2 were used. The bottom row shows the same images as those of upper but overlaid with the edges extracted from T2-TSE. Image distortion and signal piling up exist in SS-EPI (red arrow).
Figure 2: Images of patient 1 (female, 36-year-old) with microadenomas (8.3 mm) in coronal (upper) and sagittal view (bottom). From left to Right: T1-TSE, zoom-in T1-TSE, non-DW PSF-EPI, mean DWI(1 x 1 x 2 mm3, b=800 mm/s2) and ADC maps. The lesion shows hypointense in T1-TSE and hyperintense in distortion-free DWI (yellow arrows).