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The power of field strength: a direct comparison of USPIO-enhanced MRI at 3 and 7T to detect suspicious lymph nodes in patients with prostate cancer
Ansje Fortuin1,2, Sjaak van Asten1, Andor Veltien1, Bart Philips1, Thomas Hambrock1, Stephan Orzada3,4, Harald Quick3,5, Jelle Barentsz1, Marnix Maas1, and Tom Scheenen1,3
1Radboudumc, Nijmegen, Netherlands, 2Radiology, Ziekenhuis Gelderse Vallei, Ede, Netherlands, 3Erwin L Hahn Institute for MR Imaging, Essen, Germany, 4University of Heidelberg, Heidelberg, Germany, 5University of Duisburg-Essen, Essen, Germany
USPIO-enhanced MRI in 20 patients with high-risk prostate cancer identified significantly more suspicious lymph nodes at 7T compared to 3T. Although annotating lymph nodes in the pelvis is not an easy task, 7T improves the interobserver agreement in scoring suspicious nodes.
Table 2. Confusion matrices for reader scoring agreements on 99 from 410 co-identified nodes at 3T and on 159 from 601 co-identified nodes at 7T.
Figure 2. Histogram of the size of annotated nodes by Reader A, Reader T and concordant Reader A & T for both 3 and 7 Tesla USPIO-enhanced MRI of patients with prostate cancer.