Mapping of Thalamic Matrix and Core Nuclei using QSM at 9.4 Tesla
Vinod Jangid Kumar1, Klaus Scheffler1,2, Gisela E Hagberg1,2, and Wolfgang Grodd1
1Max Planck Institute for Biological Cybernetics, Tuebingen, Germany, 2Biomedical Magnetic Resonance, University Hospital and Eberhard-Karl’s University, Tuebingen, Germany
The preliminary results show lower diamagnetic and paramagnetic sources for the core nuclei. In contrast, the matrix nuclei showed observable higher values.
Fig. 4: Histogram of the mean values for the diamagnetic and paramagnetic sources of all nuclei. Each Histogram shows values for the matrix nuclei in blue color and the core nuclei in red color. Note the lower values for the core nuclei in contrast to matrix nuclei indicating the more substantial contribution of diamagnetic and paramagnetic sources, i.e., iron, myelin, and calcium in the matrix nuclei.
Fig. 1: Thalamus QSM at 9.4 T. A) QSM map (scaled between: -215.0546 to 208.2119) B1) Negative values: diamagnetic sources (i.e., Myelin, Calcium, etc.) B2) Positive values (Paramagnetic sources, i.e., Iron, etc.) Both the values are in parts per billion, i.e., ppb (magnetic strength irrelevant). The depicted color code for all views is hot. The negative Myelin map shows a homogeneous distribution of negative QSM values across the thalamus; in contrast, the positive map shows increased QSM values mainly at the posterior, lateral, and intralaminar, midline nuclei.