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PET/MR respiratory motion gating for free
Florian Wiesinger1, Timothy Deller2, Floris Jansen2, Jose de Arcos Rodriguez1, Ronny R Buechel3, Philipp A Kaufmann3, and Edwin EGW ter Voert3
1GE Healthcare, Munich, Germany, 2GE Healthcare, Waukesha, WI, United States, 3Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland
The presented method provide an accurate respiratory waveform from listmode PET data.  This can then be used for retrospective motion gating of the acquired MR and/or PET data.  The method comes for free without requiring an extra motion sensor or complicating the PET/MR imaging workflow.  
Figure 1 (animated): High temporal-framerate PET reconstruction (Δt=1s) in the transient phase ~8mins after the injection of the Ammonia PET tracer. Corresponding respiratory waveforms (bottom) obtained using either Principal Component Analysis (PCA, black) or a pencil beam navigator over the lung-liver interface (red). This patient demonstrates a deep, regular diaphragmatic breathing pattern.
Figure 2 (animated): ZTE lung images corresponding to the Ammonia PET tracer patient shown in Figure 1. Because of the deep diaphragmatic breathing the uncorrected (averaged, left) images show strong motion blurring (especially at the lung-liver interface). Soft-gated respiratory binning (7 phases, 2nd column) resolves the diaphragmatic breathing cycle into 7 phases. Most of the data are acquired in the end-expiratory phase (3rd column) also providing the sharpest image. Its Maximum Intensity Project (MIP, right) depicts the vascular anatomy and lung lesions in fine detail.