Johannes Breitling1, Andreas Korzowski1, Neele Kempa1, Philip S. Boyd1, Mark E. Ladd1, Peter Bachert1, and Steffen Goerke1
1Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany
1Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany
Reliable motion correction of CEST-MRI data could be achieved
by extending a conventional image registration algorithm by an additional identification
and mitigation of direct water saturation artefacts using a weighted averaging
of motion parameters.
Figure 2: Representative
motion pattern (black) and estimates of conventional image registration (red), RPCA+PCA_R
(blue) and proposed method (green) with the five offsets close to the water
resonance (i.e. ±0.5 ppm) highlighted (A). Corresponding image misalignment (B) and spectral error (C)
with and without motion correction (colors and black respectively).
Figure 3: Statistical analysis for n=100 different motion patterns: boxplots of the overall spectral error (A) and the maximum misalignment (B) for uncorrected (black) and motion corrected
data using the conventional image registration (red), RPCA+PCA_R (blue) or
proposed method (green).
