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Fast acquisition of 31-P creatin kinease chemical exchange rate and relaxation rates of γ-ATP and PCr in vivo human brain at 7T using MRS-FP
Mark Stephan Widmaier1, Song-I Lim2, and Lijing Xin2
1Laboratory for Functional and Metabolic Imaging, CIBM, EPFL, Lausanne, Switzerland, 2Animal Imaging and Technology, CIBM, EPFL, Lausanne, Switzerland
 This study shows preliminary results of the feasibility using MRS-FP to measure the relaxation parameters of y-ATP and PCr as well as the chemical exchange rate kCK in vivo in human brain.
The MRS-FP sequence pattern used with the 3 different fitting parts for relaxation inhomogeneity and kCK.
(a) Two step fitting procedure of the Phantom for validation. (b) 3 step procedure for in vivo data