0186
Ferumoxytol-enhanced Pulmonary MRA in Pregnancy: Evaluation of Initial Safety and Image Quality
Jitka Starekova1, Scott K Nagle1, Mark L Schiebler1, Scott B Reeder1,2,3,4,5, and Venkata N Meduri1
1Radiology, University of Wisconsin-Madison, Madison, WI, United States, 2Medicine, University of Wisconsin-Madison, Madison, WI, United States, 3Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, 4Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, 5Emergency Medicine, University of Wisconsin-Madison, Madison, WI, United States
This retrospective study summarizes our clinical experience with 70 ferumoxytol-enhanced pulmonary MRA in 66 pregnant patients. This strategy is an ionizing radiation-free, gadolinium-free alternative for the diagnosis of pulmonary embolism.
Figure 1: Ferumoxytol-enhanced MRA is safe and radiation-free alternative form of imaging for pregnant patients to exclude pulmonary embolus. Shown are ferumoxytol-enhanced 3D MRA images of 31 year old pregnant patient in 33 gestational week acquired in free breathing, in sagittal (a), axial (b) and coronal (c) view.
Figure 2: Ferumoxytol-enhanced MRA enable visualization of pulmonary thrombus. Image acquisition is performed in free breathing. Extended blood pool contrast allows for images that can be acquired in an extended temporal window and repeatedly, without need of additional contrast agent administration. Shown are 3D MRA images of 22 year old pregnant patient in 7 gestational week, in coronal (a), axial (b) and sagittal (c) view.