0205
Characterization of Apparent Exchange Rate in Human Brain White Matter
Zhaoqing Li1,2, Yi-Cheng Hsu3, and Ruiliang Bai1,2
1Interdisciplinary Institute of Neuroscience and Technology (ZIINT), School of Medicine, Zhejiang University, Hangzhou, China, HangZhou, China, 2College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, China, HangZhou, China, 3MR Collaboration, Siemens Healthcare, Shanghai, China, ShangHai, China
FEXI shows anisotropy in human brain white matter. The direction-dependence of AXR might reflect different water exchange processes between different microstructural compartments.
Figure 3: The direction dependence of AXR, σ, and ADC on WM1 (FA >0.65). The results show the averaged values (bar height, error bar width represents standard deviation) of six subjects’ AXR, σ and ADC measured along the diffusion encoding direction perpendicular (orange) and parallel (blue) to the primary eigenvector of DTI. * P < 0.05; ** P < 0.01.
Figure 4: The FA dependence of AXR, σ, and ADC. From left to right, the results of subcortical striatum ROI, WM1 (0.15 < FA < 0.5), WM2 (0.5 < FA < 0.65), and WM3 (0.65 < FA < 1) are shown. The dot and error bar width reflect the mean and standard deviation.