0307
Insight of right ventricular dysfunction and impaired efficiency via 4D flow CMR in repaired tetralogy of Fallot
Xiaodan Zhao1, Liwei Hu2, Ru-San Tan1,3, Ping Chai4, Marielle Fortier3,5, Rong Zhen Ouyang2, Shuo Zhang6, Wen Ruan1, Ting Ting Low4, Shuang Leng1, Jun-Mei Zhang1,3, Bryant Jennifer1, Lynette Teo4, Rob van der Geest7, Teng Hong Tan3,5, James W. Yip4, Ju Le Tan1,3, Yumin Zhong2, and Liang Zhong1,3
1National Heart Centre Singapore, Singapore, Singapore, 2Shanghai Children’s Medical Centre, Shanghai, China, 3Duke-NUS Medical School, Singapore, Singapore, 4National University Hospital Singapore, Singapore, Singapore, 5KK Women’s and Children’s Hospital, Singapore, Singapore, 6Philips Germany, Humburg, Germany, 7Leiden University Medical Center, Leiden, Netherlands
CMR 4D flow with right ventricle (RV) kinetic energy (KE) and flow component analyses showed reduced RV direct flow and efficiency index, increased RV residual volume, RV peak systolic, systolic and peak E-wave KE normalized to RV end-diastolic volume in rTOF compared with normal controls
Detection of rTOF with preserved EF: ROC curves comparing the diagnostic performance of RV direct flow, efficient index and RV EF with respective AUC values. rTOF: repaired tetralogy of Fallot; EF: ejection fraction; RV: right ventricle; efficiency index: effective cardiac index/RV systolic KEiEDV; KEiEDV: kinetic energy normalized to end-diastolic volume.
Demographics, left ventricular (LV) and right ventricular (RV) flow analysis parameters in controls and repaired tetralogy of Fallot (rTOF)