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Abnormal aortic hemodynamics at predilection sites for dissection in Marfan patients: a 4D flow study
Pim van Ooij1, Mitzi van Andel2, Lukas M. Gottwald1, Aart J Nederveen1, and Maarten Groenink1
1Radiology & Nuclear Medicine, Amsterdam University Medical Centers, location AMC, Amsterdam, Netherlands, 2Cardiology, Amsterdam University Medical Centers, location AMC, Amsterdam, Netherlands
Abnormally directed hemodynamics were not associated with any patient characteristics, but showed a distinct regional increase at the inner proximal descending aorta,  a well-known predilection site for aortic dissection in Marfan patients. 
Figure 3. Maps for abnormally elevated velocity (top) and abnormally directed WSS (bottom) in the Marfan cohort. Maximum incidence is delineated in the white circles.
Figure 2. a) Maps showing abnormally elevated velocity and WSS (a) are created by comparison with the control averaged and SD velocity and WSS maps. Regions of interest 1-6 are indicated in the WSS maps. b) Maps showing abnormally directed velocity and WSS are created by comparison with the control averaged velocity and WSS maps.