Safa Hoodeshenas1, Mahmoud Adam Tahboub Amawi2, Jingbiao Chen1,3, Nimish Thakral2, Kevin J. Glaser1, Bogdan Dzyubak1, Jiahui Li1, Xin Lu1, Jie Chen1, Zheng Zhu1, Patrick S. Kamath2, Vijay Shah2, Richard L. Ehman1, Sudhakar K. Venkatesh1, Douglas A. Simonetto2, and Meng Yin1
1Department of Radiology, Mayo Clinic, Rochester, MN, United States, 2Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, United States, 3The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
1Department of Radiology, Mayo Clinic, Rochester, MN, United States, 2Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, United States, 3The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
The shear stiffness of the
spleen, as assessed with MRE, is a promising biomarker for ruling-out high-risk esophageal varices in patients with
advanced liver disease, potential reducing the need for endoscopy procedures.
Figure 1. Example MRE wave images, elastograms, MRI
anatomic and upper endoscopic images in two patients; one from high-risk group (A)
and the other from low-risk group (B).
Figure 2. Receiver operating characteristic
(ROC) curves of the training and validating cohorts showing the ability of ordinal logistic models to
grade patient’s variceal severity. The predictors included in each model
are demonstrated.