BUDA-STEAM: A rapid parameter estimation method for T1, T2, M0, B0 and B1 using three-90° pulse sequence
Seohee So1, Byungjai Kim1, HyunWook Park1, and Berkin Bilgic2
1Korea Advanced Institute of Science and Technology, Daejeon, Korea, Republic of, 2Martinos Center for Biomedical Imaging, Charlestown, MA, United States
A
pulse sequence with three 90° RF pulse and blip-up/down acquisition is
introduced to simultaneously acquire spin- and stimulated-echoes for
distortion-free, fast T1, T2, M0, B0 and B1 mapping. For parameter estimation, analytic fitting and a novel
unsupervised neural network are utilized.
Figure 1 (A) Pulse sequence diagram and phase diagram of the
proposed method. (B) Sequence diagrams of blip-up/down acquisition and
schematic diagram of reconstructing distortion-free image from the blip-up/down
images. (C) Schematic diagram of echo-shifting with echo-shifting factor of
six.
Figure 2 (A) Spin echo
and stimulated echo signal evolutions of four different tissues with five [TE,
TM] combinations. (B) Schematic diagram of analytic fitting process. (C)
Schematic diagram of unsupervised parameter estimation with neural network (a) and
detailed structure of the quantification network (b). As input of Bloch
generator, outputs of quantification network, B1 from analytic
fitting and brain mask are used.