0373
Noise reduction in diffusion weighted MRI of the pancreas using an L1-regularized iterative SENSE reconstruction
Omar Kamal1,2, Sean McTavish1, Felix Harder1, Anh T. Van1, Johannes M. Peeters3, Kilian Weiss4, Marcus R. Makowski1, Dimitrios C. Karampinos1, and Rickmer F. Braren1
1Department of Diagnostic and Interventional Radiology, Technical University of Munich, Munich, Germany, 2Department of Radiology, South Egypt Cancer Institute, Assiut, Egypt, 3Philips Healthcare, Best, Netherlands, 4Philips GmbH, Hamburg, Germany
The L1-regularized iterative SENSE reconstruction of pancreas single shot DW-EPI significantly reduces the noise band-like artifacts at high acceleration factors and allows more stable and robust ADC quantification (less noise bias) even when including fewer number of averages. 
Figure 1: DWI b600 images of the pancreas using the SENSE reconstruction (a) and the L1-regularized SENSE reconstruction (b) in a healthy pancreas. The central noise artifact seen with SENSE (yellow arrowheads) overlapping the pancreas (black star) is significantly reduced in the L1-regularized SENSE.