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Rapid dynamic speech imaging at 3Tesla using combination of a custom airway coil, variable density spirals and manifold regularization
Rushdi Zahid Rusho1, Wahidul Alam1, Abdul Haseeb Ahmed2, Stanley J. Kruger3, Mathews Jacob2, and Sajan Goud Lingala1,3
1Roy J. Carver Department of Biomedical Engineering, The University of Iowa, Iowa City, IA, United States, 2Department of Electrical and Computer Engineering, The University of Iowa, Iowa City, IA, United States, 3Department of Radiology, The University of Iowa, Iowa City, IA, United States
We propose a novel high-speed speech MRI scheme that combines multi-coil acquisitions from a 16 channel airway coil, variable density spirals, and manifold regularization. We demonstrate efficient reconstruction of complex free running speech at a temporal resolution of 15 ms/frame.
Figure 5 (animation): Comparison of manifold regularization and low rank regularization schemes reconstructed using 3arms/frame (or time resolution of 15 ms). Shown are the dynamic animations and temporal profile cuts from two subjects. We observe good fidelity and under-sampling artifact robustness in the manifold scheme compared to the low rank scheme. This is attributed to efficiently exploiting the similarities in local or distant image frames within the dataset without any explicit binning strategies.
Figure 2: Dynamic images can be modeled as points on a smooth nonlinear manifold embedded in a high dimensional ambient space. This is demonstrated in the dynamic free speech task of serially counting numbers. Similar images are neighbors on the 2D manifold even if they occur at different times (see red and green squares), whereas dissimilar images are distant on the 2D manifold even if they occur consecutively in time. The manifold regularization thus exploits the similarity of points that are close to each other on this manifold.