0444
Algebraic reconstruction of missing data in zero echo time MRI with pulse profile encoding (PPE-ZTE)
Romain Froidevaux1, Markus Weiger1, and Klaas Paul Pruessmann1
1Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Zurich, Switzerland
We demonstrate a method for algebraic reconstruction of ZTE datasets with large central gaps, based on the knowledge of the excitation pulse. It enables the use of longer pulses and overcomes flip angle limitations. Results include phantom and in-vivo imaging.
Fig. 3: ZTE MRI of a water bottle using long RF excitation pulses. In conventional ZTE, for gaps ≥ 4 dk, amplification of noise and aliased signal create artifacts that dominate the images. However, PPE-ZTE preserves image quality, even with long sweep pulses. The linear grey-scaling is normalized to the maximum of each image separately.
Fig. 5: In-vivo PPE-ZTE MRI in the head. ZTE is limited to proton-density contrast due to the low flip angle reached with short block pulses, even at maximum power. However, PPE-ZTE allows the use of longer sweep pulses that create larger flip angles and consequently T1 contrast, in this case mostly between the cerebrospinal fluid and brain tissues. Furthermore, short-T2 signal of the eye lenses stands out against the vitreous body. Remaining low intensity variation are likely to stem from residual model violations.