0520
Quantification of Synovial Fluid using Magnetic Resonance Fingerprinting Multicomponent Imaging in Articular Cartilage of Knee
Seung Eun Lee1, Joon-Yong Jung1, and Dongyeob Han2
1Seoul St. Mary’s Hospital, Seoul, Korea, Republic of, 2Siemens Healthineers, Seoul, Korea, Republic of
In ex vivo experiment and clinical study, we demonstrated that SFF map generated by multicomponent MRF framework can quantify synovial fluid in small cartilage defect, and provides direct information on cartilaginous water content.
Figure 1. Cartilage segmentation on bovine cartilage in normal cartilage (A), cartilage with 0.6mm holes (B), 0.9mm holes (C) and 1.2mm holes (D). (E, F) Segmentation area indicated with colors in sagittal plane and leg specimen. (G) Result of cartilaginous fluid fraction in each location.
Figure 3. Knee cartilage segmentations of 3D FSE image and PD map in osteoarthritis patient. A cartilage defect in posterior medial femoral condyle is demonstrated in 3D FSE image (green arrow) and shows good correlation with fluid exclusion image (FEI) on SFF map, better than FEI on T2 map.