0554
Rapid Parametric Mapping Using the Unsuppressed Water Signals in Metabolic Imaging of the Brain
Rong Guo1,2, Yibo Zhao1,2, Yudu Li1,2, Yao Li3, and Zhi-Pei Liang1,2
1Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 2Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 3School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China
This work presents a new method to achieve fast T1 and T2 mapping in 1H-MRSI experiments using SPICE without water suppression. With a novel data acquisition and processing scheme, T1 and T2 maps at 1.0×1.0×2.0 mm3 were obtained successfully in one-minute extra scan time.
Figure 5. A set of representative results from a healthy subject using the proposed method. High-resolution T1, T2, PD maps at 1.0×1.0×2.0 mm3 resolution and metabolite distributions (NAA, Cr, Cho, …) maps at 2.0×3.0×3.0 mm3 resolution were obtained in a total 8-minute scan.
Figure 4. In vivo 3D high-resolution T1 and T2 maps obtained from a healthy subject with one extra minute scan time.