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4D Phase Contrast MRI detects heterogeneous strain rate patterns along the length of the Tibialis Anterior muscle during dynamic contractions
Thom T. J. Veeger1, Gustav J. Strijkers2, Valentina Mazzoli3, Hans C. van Assen1, Jurriaan H. de Groot4, Lukas M. Gottwald5, Aart J. Nederveen5, Hermien E. Kan1,6, and Melissa T. Hooijmans2
1Radiology, Leiden University Medical Center, Leiden, Netherlands, 2Biomedical Engineering & Physics, Amsterdam Movement Sciences, Amsterdam University Medical Center, Location AMC, Amsterdam, Netherlands, 3Radiology, Stanford University, Stanford, CA, United States, 4Rehabilitation Medicine, Leiden University Medical Center, Leiden, Netherlands, 5Radiology and Nuclear Medicine, Amsterdam Movement Sciences, Amsterdam University Medical Center, Location AMC, Amsterdam, Netherlands, 6Duchenne Center Netherlands, Veenendaal, Netherlands
Spatially heterogeneous strain rates were detected along the length of the TA muscle during movement, with smallest and largest positive and negative strain rate eigenvalues in the most proximal and distal muscle segment, respectively.
Fig. 2) Sagittal (top) and axial (bottom) phase contrast velocity images (left) and local expansion (middle) and contraction (right) rate maps of a representative subject for the load condition during maximal dorsiflexion velocity.
Fig. 4) Line graphs showing local contraction and expansion rate during dorsi-/plantarflexion without and with load for five muscle segments. Individual subjects are indicated with grey lines (connecting with and without load conditions) and in black the mean and standard deviation of the group per segment and per load condition. Significant differences in local expansion and contraction rates between proximodistal segments are shown with hooked lines. Additionally, at the bottom, muscle area in number of voxels is shown as a percentage of muscle length (distal 0-100 proximal).