Manuel Taso1, Fanny Munsch1, Olivier M Girard2, Guillaume Duhamel2, David C Alsop1, and Gopal Varma1
1Division of MRI research, Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States, 2CRMBM, Aix-Marseille Univ, CNRS, Marseille, France
1Division of MRI research, Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States, 2CRMBM, Aix-Marseille Univ, CNRS, Marseille, France
We implemented a CSF-suppressed FSE sequence for myelin imaging using ihMT (FLAIR-ihMT). Simulations and experiments show the benefits of FSE imaging compared to gradient-echo, and the CSF suppression improves robustness of FSE imaging for ihMT myelin imaging in the CNS.
Figure 4 – 1.6mm high-resolution ihMT and ihMTR. A volume reconstructed with half-sampling is also shown
Figure 3 – (a) ihMT-RAGE vs ihMT-FSE vs FLAIR-ihMT. Red arrows show area of improvement with FLAIR-ihMT compared to both ihMT-RAGE and FSE (b) comparison of ihMT image quality in infratentorial regions and (c) normalized ihMT signal comparison