Frederick A Bagdasarian1,2, Xuegang Yuan1,2, and Samuel Colles Grant1,2
1National High Magnetic Field Laboratory, Florida State University, Tallahassee, FL, United States, 2Chemical & Biomedical Engineering, FAMU-FSU College of Engineering, Tallahassee, FL, United States
1National High Magnetic Field Laboratory, Florida State University, Tallahassee, FL, United States, 2Chemical & Biomedical Engineering, FAMU-FSU College of Engineering, Tallahassee, FL, United States
Human mesenchymal stem cells promote recovery of diffusion metrics after ischemic stroke via DTI, NODDI and DKI analysis. Differences in recovery are evident between white and grey matter.
Intracellular
volume fraction (ICVF) and orientation dispersion index (ODI) for the
ipsilateral external capsule and striatum. Representative NODDI maps are
provided for a specimen from the hMSC group. * with bracket = significant
difference between treatment groups, + = significant difference between
treatment group & naïve. #, ¥ and ● = significant difference within group
from D3, 7 and 21, respectively. Significance level set at p<0.05.
Mean,
Axial and Radial Diffusivity (MD, AD, RD) and Fractional Isotropy for the
ipsilateral external capsule and striatum. Representative DTI maps are provided
for a specimen from the hMSC group. * with bracket = significant difference between
treatment groups, + = significant difference between treatment group & naïve.
#, ¥ and ● = significant difference within group from D3, 7 and 21,
respectively. Significance level set at p<0.05.
