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ADC Decreases in Solid Tumors Following Monotherapy With PEGylated Recombinant Human Hyaluronidase: Results From Early-Phase Clinical Trials
Andres Mauricio Arias-Lorza1 and Natarajan Raghunand1
1Moffitt Cancer Center, Tampa, FL, United States
ADC decreases in solid tumors following monotherapy with PEGylated Recombinant Human Hyaluronidase PEGPH20.
Figure 4. ADC changes in muscle tissue (top) and Bland-Altman plot of ADC repeats differences at muscle.
Figure 3. Bland-Altman plot describing median ADC repeatability. Each marker/color represents a baseline repeat difference at each tumor. RC obtained per tumor is used to distinguish true changes in that tumor. In case the patient does not have more than one repeat at baseline, the full data RC given by the dashed lines is used instead.