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Heterogeneity of Viscoelastic Properties in Prostate Cancer Assessed by Ex Vivo MR Elastography
Rolf Reiter1,2, Shreyan Majumdar2, Steven Kearney2, Andre Kajdacsy‐Balla3, Virgilia Macias3, Michael Abern4, Simone Crivellaro4, Thomas J. Royston2, and Dieter Klatt2
1Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany, 2Bioengineering, University of Illinois at Chicago, Chicago, IL, United States, 3Pathology, University of Illinois at Chicago, Chicago, IL, United States, 4Urology, University of Illinois at Chicago, Chicago, IL, United States
We aimed to evaluate the heterogeneity of viscoelastic tissue properties of fresh prostatectomy specimens using MR elastography. Our results suggest that prostate cancer is characterized by a stiff yet homogeneous biomechanical signature. 
Figure 1. Coefficient of variation (CV) vs. magnitude of the complex shear modulus (|G*|) for healthy (blue circles) and cancerous segments (red crosses). The line shows linear correlation with r = -0.48 and p < 0.001.