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A viscoelastic phantom of the healthy human liver for elastography in MRI and ultrasound
Anna Morr1, Helge Herthum1, Felix Schrank1, Steffen Görner1, Jürgen Braun1, Ingolf Sack1, and Heiko Tzschätzsch1
1Charité - Universitätsmedizin Berlin, Berlin, Germany
The proposed elastography phantom has viscous and elastic properties in a wide frequency range similar to that of the human liver. The novel phantom facilitates technical developments and improvements of MRE and USE.
Comparison of the proposed phantom with in vivo literature data and conventional phantoms by means of shear wave speed (SWS) and penetration rate (PR). The CIRS phantom showed no measurable shear wave damping (due to an inverse relation between damping and PR, this corresponds to an infinity PR). Therefore, the PR for CIRS phantom was not shown.
Setup and post processing for USE and clinical MRE. A vibration plate was inserted in the phantom to create plane shear waves. Shear wave fields for all vibration frequencies are acquired within the $$$x-z$$$-plane. After frequency selection by Fourier transformation a profile was drawn parallel to the wave propagation (shown wave fields based on MRE). Viscoelastic properties (shear wave speed, penetration rate) are obtained by fitting profile data (circles) with a damped complex shear wave (solid lines).