1032
Anisotropic Mechanical Properties of White Matter Tracts Estimated with Multi-Excitation MRE and TI-NLI
Daniel R. Smith1, Diego A. Caban-Rivera1, Matthew D. J. McGarry2, L. Tyler Williams1, Grace McIlvain1, Charlotte Guertler3, Ruth J. Okamoto3, Damian Sowinski2, Elijah Van Houten4, Phil V. Bayly3, Keith D. Paulsen2, and Curtis L. Johnson1
1Biomedical Engineering, University of Delaware, Newark, DE, United States, 2Thayer School of Engineering, Dartmouth College, Hanover, NH, United States, 3Mechanical Engineering and Materials Science, Washington University in St. Lous, St. Louis, MO, United States, 4Mechanical Engineering, Universite de Sherbrooke, Sherbrooke, QC, Canada
Using multi-excitation MRE and TI-NLI, we estimated and found significant differences in the anisotropic mechanical properties, substrate shear modulus μ, shear anisotropy φ, and tensile anisotropy ζ, within individual regions of interest of the human brain.
Figure 3: Representative slice for each subject investigated showing each of the three anisotropic material parameters: μ, φ, and ζ.
Figure 4: Representation of the three anisotropic material parameters (μ, φ, ζ) in WM tracts: corpus callosum (CC), corona radiata (CR), and superior longitudinal fasciculus (SLF).