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Increased Saturated Fatty Acid Fraction in the Adipose Tissue Near Malignant Tumors in Breast Cancer Patients
Mehran Baboli1, Pippa Storey2, Terlika Pandit Sood2, Justin Fogarty2, Melanie Moccaldi2, Alana Lewin2, Linda Moy2, and Sungheon Gene Kim1
1Radiology, Weill Cornell Medicine, New York, NY, United States, 2Radiology, NYU Langone Health, New York, NY, United States
The SFA was significantly higher around the malignant tumor than on the contralateral normal breast while no significant changes were observed in benign tumors. The results showed that the SFA could potentially be used to understand the role of adipose tissue and the development of breast cancer
Figure 2: Examples of the SFA maps in contra- and ipsilateral breast and small ROI around the tumor. Only the voxels with >90% fat fraction were included in the maps.
Figure 3: SFA comparison between contralateral, ipsilateral breast, and a small ROI around the lesions for patients with (a) benign and (b) malignant lesions. A significantly higher (p= 0.007) SFA was observed around the malignant lesions.