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The Performance of Breast Diffusion Tensor Imaging in the Evaluation of Pre-Surgical Treatment of Breast Cancer.
Anabel M Scaranelo1, Edna Furman-Haran2, Abdullah Alabousi3, Dov Grobgeld2, Vivianne Freitas1, and Hadassa Degani4
1Medical Imaging, University of Toronto, Toronto, ON, Canada, 2Weizmann Institute of Science, Rehovot, Israel, 3Department of Radiology, St Joseph's Healthcare. McMaster University, Hamilton, ON, Canada, 4DDE MRI Solutions Ltd., Tel Aviv, Israel
We have investigated the capability of breast DTI-MRI parameters to monitor and quantitatively evaluate response to neoadjuvant systemic therapy in the four major breast cancer biological subtypes. DTI shows correlation with surgical pathology size and detected pCR in all subtypes.