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Multiparametric MRI of Renal Tissue Shows Dietary Differences Between Survivors and Non-survivors in Sepsis-associated Acute Kidney Injury
Wan-Ting Zhao1,2,3, Karl-Heinz Herrmann1, Martin Krämer1, Renat Sibgatulin1, Ali Nahardani1,2, Jürgen R. Reichenbach1, and Verena Hoerr1,2,4
1Medical Physics Group,Institute of Diagnostic and Interventional Radiology, University Hospital Jena, Jena, Germany, 2Center for Sepsis Control and Care, University Hospital Jena, Jena, Germany, 3Institute of Medical Microbiology, University Hospital Jena, Jena, Germany, 4Clinic for Radiology, University Hospital Muenster, Muenster, Germany
(1.   Animals having received protein-rich diet showed lowest mortality rate.(2.   Survivors having received protein-rich diet showed increased cortical T1 and T2 value compared to healthy rat.Scatter plot of cortical T2 and perfusion can distinguish between survivors and non-survivors
Figure 4: Compilation of cortical and medullary results of perfusion as well as T1 and T2 relaxation time for all experimental groups (survivors, non-survivors, healthy sham group) and statistical evaluation using the Mann-Whitney U-test(*: p<0.05, **:p<0.01).
Figure 3:Cortical and medullary perfusion as well as T1 and T2 values in correlation with the severity score based on data from all experimental groups (3 different diets in both the PCI- and sham-group).