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Radial tiny golden angle MRI combined with Cardiac and Respiratory Self-Gating in the Small Animal model – one acquisition, many possibilities
Patrick Metze1, Hao Li2, and Volker Rasche1,2
1Internal Medicine II, Ulm University Medical Center, Ulm, Germany, 2Core Facility Small Animal Imaging (CF-SANI), Ulm University, Ulm, Germany
Radial tiny golden angle MRI allows for reconstruction of high-quality respiratory and cardiac gated images and sliding-window real-time imaging from the same continuous acquisition, enabling e.g. simultaneous perfusion and function assessment.
Figure 4: Continuous tyGA acquisition with simultaneous administration of contrast agent. a) and c) show image ROI and k-space intensities over the whole acquisition, b) shows the image intensities around the timepoint of administration. d) shows example sliding-window images and e) and f) correspond to dual gated reconstructions before and after contrast administration. Row-wise differences indicate different respiration stages, column-wise differences show the influence of the cardiac phase.
Figure 3: Self-gated reconstructions of an exemplary cardiac (SAx) and lung (coronal) acquisition. Due to the properties of the tyGA trajectory, artefact levels for respiratory ungated cardiac imaging is very low. However, differences to respiratory gated imaging can not only be seen in the vessels, but also in the heart itself. Cardiac gating seems mandatory for lung imaging, as shape and position of vessels clearly change with the heartbeat and could influence functional measurements.