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BOLD-free fMRI?
Tobias C Wood1 and Nikou Louise Damestani1
1Neuroimaging, King's College London, London, United Kingdom
We demonstrate a proof-of-concept fMRI experiment using a BOLD-insensitive MT-prepared ZTE pulse sequence, which exploits the recently proposed Arterial Blood Contrast mechanism. We show tightly localised responses to a visual checkerboard task in a small number of subjects.
Figure 4: Results of the single-subject analyses overlaid in MNI space. At both 480° and 500° power levels focal activation in the visual cortex can be observed. At 0° MT power, apparent activation can be observed in the sagittal sinus, most likely due to blood volume changes within the sinus.
Figure 3: Temporal SNR achieved for the three different power levels. The reduction of signal due to MT leads to a notable fall in tSNR.