Ethan Danielli1,2, David Stillo1,2, Rachelle Ho3,4, Carol DeMatteo3,5, Geoffrey B Hall4, Nicholas A Bock4, John F Connolly1,4,5,6, and Michael D Noseworthy1,2,5,7,8
1School of Biomedical Engineering, McMaster University, Hamilton, ON, Canada, 2Imaging Research Centre, St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada, 3School of Rehabilitation Sciences, McMaster University, Hamilton, ON, Canada, 4Department of Psychology, Neuroscience & Behaviour, McMaster University, Hamilton, ON, Canada, 5ARiEAL Research Centre, McMaster University, Hamilton, ON, Canada, 6Department of Linguistics, McMaster University, Hamilton, ON, Canada, 7Department of Electrical and Computer Engineering, McMaster University, Hamilton, ON, Canada, 8Department of Radiology, McMaster University, Hamilton, ON, Canada
1School of Biomedical Engineering, McMaster University, Hamilton, ON, Canada, 2Imaging Research Centre, St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada, 3School of Rehabilitation Sciences, McMaster University, Hamilton, ON, Canada, 4Department of Psychology, Neuroscience & Behaviour, McMaster University, Hamilton, ON, Canada, 5ARiEAL Research Centre, McMaster University, Hamilton, ON, Canada, 6Department of Linguistics, McMaster University, Hamilton, ON, Canada, 7Department of Electrical and Computer Engineering, McMaster University, Hamilton, ON, Canada, 8Department of Radiology, McMaster University, Hamilton, ON, Canada
Decreased FA was significantly correlated with younger age and higher PCSS scores. Increased RD was significantly correlated with younger age and the interaction between time to scan and Post-Concussion Symptom Scale (PCSS) score.
Figure 1. Plots of significant findings between DTI metrics and demographic information. Top left: Total FA injury burden versus Age; Top Right: Total FA injury burden versus PCSS Score; Bottom Left: Total RD injury burden versus Age; Bottom Right: A paired matrix plot indicating the distribution of each metric and the correlation between metrics.
Table 1. Results for the multilinear regression of demographic and DTI metrics.
