Zijing Dong1,2, Fuyixue Wang1,3, Lawrence L. Wald1,3, and Kawin Setsompop4,5
1Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 2Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA, United States, 3Harvard-MIT Health Sciences and Technology, MIT, Cambridge, MA, United States, 4Department of Radiology, Stanford University, Stanford, CA, United States, 5Department of Electrical Engineering, Stanford University, Stanford, CA, United States
1Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 2Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA, United States, 3Harvard-MIT Health Sciences and Technology, MIT, Cambridge, MA, United States, 4Department of Radiology, Stanford University, Stanford, CA, United States, 5Department of Electrical Engineering, Stanford University, Stanford, CA, United States
A powerful technique, ACE-EPTI, is presented for dMRI and diffusion-relaxometry with high SNR-efficiency, high image quality without distortion/blurring, self-navigated phase correction, capability for time-resolved multi-contrast imaging, and fast acquisition with only 3-shot.
Figure 1. Illustration of the echo-train shifted acquisition, 3-shot spatiotemporal encoding and subspace reconstruction of ACE-EPTI.
Figure 4. Reconstructed images and SNR maps of ss-EPI and 3-shot ACE-EPTI from the phantom and in-vivo experiments. For ACE-EPTI, the echo-combined image is shown and is used for the SNR analysis. The images acquired by ss-EPI show obvious distortion in the front part of phantom and brain (yellow arrows), while ACE-EPTI eliminates all these distortion artifacts. ACE-EPTI also shows a 30-40% increase in SNR when compared to a time-matched ss-EPI with 3 average in both phantom and in-vivo experiments.