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Navigator-Free Submillimeter Diffusion MRI using Multishot-encoded Simultaneous Multi-slice (MUSIUM) Imaging
Wei-Tang chapel Chang1, Khoi Minh Huynh2, Pew-Thian Yap1, and Weili Lin2
1Radiology, UNC at Chapel Hill, Chapel Hill, NC, United States, 2BRIC, UNC at Chapel Hill, Chapel Hill, NC, United States
MUSIUM sequences enhance SNR with low RF power and peak amplitude and are motion robust and free from slab boundary artifacts. The efficacy of MUSIUM imaging is demonstrated at 0.86 mm isotropic resolution, revealing detailed structures in cortical areas.
Figure 3: The reconstruction results of the 0.86-mm isotropic MUSIUM data. (a) The diffusion images at b=500, 1000 and 2000. (b) The FA map in three orthogonal planes. The data acquisition time is ~12.5 minutes.
Figure 1: The RF excitation and k-space sampling trajectories of the MUSIUM sequences. (a) The RF excitation of a MUSIUM sequence. nsms × nshot slices are excited simultaneously. (b) The sampling trajectories of MUSIUM sequence.