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Multi-shot diffusion MRI of the human brain with motion-compensated oscillating gradients
Eric Seth Michael1, Franciszek Hennel1, and Klaas Paul Pruessmann1
1Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Zurich, Switzerland
The use of motion-compensated oscillating diffusion gradients permitted high-resolution, interleaved acquisitions of the in-vivo human brain.  This implementation produced images void of visible artifacts without the use of additional computational techniques.
Figure 4. Time series of DW three-shot images across dynamics for all gradient shapes (left), and the complex average across dynamics (right). All images capture the same slice of one subject. The diffusion-sensitizing gradient was aligned with the z-direction. Significant artifacts confound each dynamic and the subsequent average for PGSE acquisitions; no such issue occurs for either OGSE acquisition, for which fine anatomical detail can be seen.
Figure 2. Phase differences with respect to the first dynamic (different columns) across subsequent single-shot dynamics for each diffusion sensitization scheme (different rows). Phase is observed to have more pronounced fluctuations (i.e., of greater magnitude) among PGSE dynamics than among dynamics of either OGSE acquisition. Between both forms of OGSE, phase variations are similar.