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Optimising spiral diffusion tensor cardiovascular magnetic resonance for high resolution ex-vivo STEAM imaging on a clinical scanner
Malte Roehl1,2, Peter D Gatehouse1,2, Pedro F Ferreira1,2, Sonya V Babu-Narayan1,2, David N Firmin1,2, Dudley J Pennell1,2, Sonia Nielles-Vallespin1,2, and Andrew D Scott1,2
1National Heart and Lung Institute, Imperial College London, London, United Kingdom, 2Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, United Kingdom
Ex-vivo diffusion tensor cardiovascular magnetic resonance provides insights into cardiac microstructure and validation of in-vivo methods. To overcome limitations of current EPI methods we present an interleaved spiral approach, yielding good image quality at high resolution.
Figure 5:Comparison of HA, E2A, MD and FA for a single midventricular slice in a porcine ex vivo heart using a spiral readout and an EPI readout. Both using the same STEAM approach, multiple averages (both using complex averaging) and the same total acquisition time of 2hours.
Figure 4:A) DT-CMR maps reconstructed from data acquired with similar total acquisition duration, but increasing numbers of spiral interleaves/decreasing numbers of interleaves. Total acquisition time was 2h for rows 1-4. B) Plot of mean transmural HA-R2 of the data shown in A. C) Plot of Transverse Angle standard deviation of the data shown in A.