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Prospective motion-corrected three-dimensional multiparametric mapping of the brain
Shohei Fujita1,2, Naoyuki Takei3, Akifumi Hagiwara1, Issei Fukunaga1, Dan Rettmann4, Suchandrima Banerjee5, Ken-Pin Hwang6, Shiori Amemiya2, Koji Kamagata1, Osamu Abe2, and Shigeki Aoki1
1Department of Radiology, Juntendo University, Tokyo, Japan, 2Department of Radiology, The University of Tokyo, Tokyo, Japan, 3MR Applications and Workflow, GE Healthcare, Tokyo, Japan, 4MR Applications and Workflow, GE Healthcare, Rochester, MN, United States, 5MR Applications and Workflow, GE Healthcare, Menlo Park, CA, United States, 6Department of Radiology, MD Anderson Cancer Center, Houston, TX, United States
High linearity of T1 and T2 values in a phantom was obtained with and without motion correction. The repeatability and accuracy of T1 and T2 quantification were improved under in-plane and through-plane motions.
Figure 3. Representative motion tracking and quantitative maps of a healthy volunteer with intentional in-plane (“side-to-side”) head motions. The head motion was rigidly tracked in three translational and three rotational directions. (a) Motion tracking time curve of translations and rotations in the x-y-z coordinate system. (b) T1 and T2 maps acquired with the proposed method and those without motion correction are shown.
Figure 5. Effect of motion correction on regional quantitative values. (a) Bland-Altman plots representing the bias of scans with motion with and without motion correction compared with scans without motion as references. Data points with motion correction are closer to zero than those without, indicating smaller bias achieved by motion correction. (b) Coefficients of variation (CV) represent the repeatability of the scans. In both T1 and T2, within-subject CVs were smaller, indicating higher repeatability, in motion-corrected scans than those without motion correction.