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Cortical Mapping and T1-Relaxometry using Motion Corrected MPnRAGE: Test-Retest Reliability with and without Motion Correction
Steven Kecskemeti1, Abigail Freeman1, and Andrew L Alexander1
1University of Wisconsin-Madison, Madison, WI, United States
Retrospectively motion corrected MPnRAGE demonstrated high test-retest of R1 relaxometry of the cortex, as well as FreeSurfer measures of cortical thickness, surface area, and volume.  High test-retest of pediatric subjects was found with 100% data acceptance. 
Figure 1: Example images and motion estimations from a 7.6 year old typically developing female demonstrating MPnRAGE motion correction for moderate to severe motions. Without motion correction, the T1-weighted and quantitative R1 images have blurred tissue boundaries.
Figure 3. The regional surface maps for the coefficients of variations x 100 without (top) and with (bottom) motion correction.