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Highly accelerated T1ρ imaging using kernel-based low-rank compressed sensing reconstruction in knees with and without osteoarthritis
Jeehun Kim1,2, Chaoyi Zhang3, Mingrui Yang1, Hongyu Li3, Mei Li1, Richard Lartey1, Leslie Ying3,4, and Xiaojuan Li1
1Department of Biomedical Engineering, Program of Advanced Musculoskeletal Imaging (PAMI), Cleveland Clinic, Cleveland, OH, United States, 2Department of Electrical Engineering, Case Western Reserve University, Cleveland, OH, United States, 3Electrical Engineering, University at Buffalo, State University of New York, Buffalo, NY, United States, 4Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, NY, United States
Compared to reference images, cartilage T coefficients of variation < 3.5% was achieved with prospective acceleration factor of 8, which reduced the scan time to 3 minutes, for subjects with and without osteoarthritis.
Figure 4 Sample images of reference and accelerated T map. The T map of cartilage compartments was overlaid to the corresponding DESS images for better visualization.
Figure 3 (a) shows the CV between reference and accelerated T value, scan-rescan CV, and scan-rescan ICC with a 95% confidence interval. (b) shows the Bland-Altman plot between accelerated and reference T value. Each entry corresponds to an average value of a cartilage compartment in a subject. ICC was calculated for each AF.