Fast 3D steady state inhomogeneous magnetization transfer imaging with Segmented Spoiled Gradient Echo - Echo Planar Imaging.
Masanori Ozaki1 and Masao Yui1
1Research and Development Center, Canon Medical Systems Corporation, Kawasaki, Japan
Inhomogeneous magnetization transfer can
produce myelin-specific contrast, however long acquisition times are necessary for
acquisitions with whole-brain coverage. Our proposed method achieved reduced
acquisition times without SNR penalty compared to previous reports.
Figure 2. Representative maps of: a,c) ihMTR;
b,d) ihMTRinv; a,b) maps calculated by 3D segmented SPGR dataset and
c,d) maps calculated by 3D segmented SPGR-EPI dataset from a healthy volunteer,
as acquired in the sagittal plane, and reformatted into the coronal and axial
planes.
Figure 1. Sequence diagrams used to acquire
data for: a) ihMT, and b) reference using a T1 preparation.