1506
Aberrant spontaneous low-frequency brain activity in patients with subjective cognitive decline: A resting-state fMRI study
Yin Tang1, Ling Zhang1, Yi Zhu2, Hongyuan Ding1, Yaxin Gao2, Long Qian3, Weiqiang Dou3, and Ming Qi1
1Radiology department, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 2Rehabilitation Department, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 3MR Research China, GE Healthcare, Beijing, China
In this study ALFF changes have been investigated for patients with SCD ,MCI and HCs. Lower ALFF values have been found at the right supramarginal gyrus, left precuneus and right supplementary motor area for SCD and MCI patients than HCs and the ALFFs also showed correlations with clinical scales. 
Figure 1. Lower ALFF values at the right supramarginal gyrus and left precuneus region in MCI than HC.
Figure 2. The ALFF values in SCD group were significantly lower than those in HC group for the right supramarginal gyrus, left precuneus and right supplementary motor area.